The data analyzed in this paper are part of the results described in Bueno et al. (2000). Three cytogenetics endpoints were analyzed in three populations of a species of wild rodent – Akodon montensis – living in an industrial, an agricultural, and a preservation area at the Itajaí Valley, State of Santa Catarina, Brazil. The polychromatic/normochromatic ratio, the mitotic index, and the frequency of micronucleated polychromatic erythrocites were used in an attempt to establish a genotoxic profile of each area. It (...) was assumed that the three populations were in the same conditions with respect to the influence of confounding factors such as animal age, health, nutrition status, presence of pathogens, and intra- and inter-populational genetic variability. Therefore, any differences found in the endpoints analyzed could be attributed to the external agents present in each area. The statistical models used in this paper are mixtures of negative-binomials and Poisson variables. The Poisson variables are used as approximations of binomials for rare events. The mixing distributions are beta densities. The statistical analyzes are under the bayesian perspective, as opposed to the frequentist ones often considered in the literature, as for instance in Bueno et al. (2000). (shrink)

RESUMO A alimentação é o fator que mais onera um sistema de produção animal. Assim, a utilização de diferentes estratégias de alimentação dos animais ainda é o grande desafio da nutrição animal, principalmente, levando em consideração as exigências nutricionais de diferentes categorias de ruminantes, em especial bovinos em regiões tropicais, haja vista que a sazonalidade na produção de forragens afeta diretamente a produção bovina, promovendo inadequação no atendimento das exigências nutricionais dos animais principalmente em minerais e vitaminas. Uma alimentação que (...) não atenda as exigências nutricionais dos ruminantes gera prejuízos no sistema de produção, além de, em casos mais graves, ocasionar a perda do animal. Estudos que abordam o efeito e a importância de vitaminas e minerais na nutrição bovina são escassos e necessários. Recentemente a National Research Council (NRC) apresentou novos registros das exigências nutricionais das vitaminas e minerais. Essas alterações proporcionam um impacto econômico significativo em relação à nutrição animal. Nesse sentido, objetivou-se com esta revisão trazer informações acerca de vitaminas e minerais na nutrição de bovinos em pastejo. -/- Palavras-chave: Alimentação animal; forragem; pastagem; requerimentos nutricionais; ruminantes; vitaminas lipossolúveis (Source: AGROVOC). -/- ABSTRACT Animal feed is the factor that most burdens a production system. Thus, the use of different animal feeding strategies is still the great challenge of animal nutrition, taking into account the nutritional requirements of different categories of ruminants, especially cattle in tropical regions, given that seasonality in forage production directly affects cattle production, promoting inadequacy in meeting the nutritional requirements of animals, mainly in minerals and vitamins. A diet that does not meet the nutritional requirements of ruminants generates losses in the production system, in addition to, in more serious cases, causing the loss of the animal. Studies that address the effect and importance of vitamins and minerals in bovine nutrition are scarce and necessary. Recently the National Research Council (NRC) presented new records of the nutritional requirements of vitamins and minerals. These changes provide a significant economic impact on animal nutrition. In this sense, the objective of this review was to bring information about vitamins and minerals in the nutrition of grazing cattle. -/- Keywords: Animal feeding; fat soluble vitamins; forage; nutritional requirements; pasture feeding; ruminants (Source: AGROVOC). -/- REFERÊNCIAS BIBLIOGRÁFICAS -/- 1. Cavalcanti CPL, Silva e Macedo TJ, Gois GC, Menezes VG, Monte APO, Silva AD, Silva DJM, Silva EO, Araújo GGL, Rodrigues RTS, Wischral A, Matos MHT, Queiroz MAA. 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Avaliação dos efeitos de fontes de fósforo na dieta sobre parâmetros do meio ruminal e eficiência de síntese microbiana, digestibilidade dos nutrientes e fósforo plasmático em bovinos. Rev Bras Zootec. 2009; 38:760-769. 34. Yamada S, Inaba M. Potassium metabolism and management in patients with CKD. Nutr. 2021; 13:1-19. 35. Martinsen TC, Fossmark R, Waldum HL. The phylogeny and biological function of gastric juice—Microbiological consequences of removing gastric acid. Int J Mol Sci. 2019; 20:1-22. 36. González FHD, Silva SC. Minerais e vitaminas no metabolismo animal. 1st ed. Porto Alegre: Universidade Federal do Rio Grande do Sul; 2019. 37. Melo RR, Gonçalves SLS, Baccarin FJB, Vasconcelos WA, Miranda SC. Influência de altas dosagens de cloreto de potássio no desenvolvimento de espécies em cultivo hidropônico. Pubvet. 2020; 14:1-9. 38. Araújo WAG, Rostagno HS, Albino LFT, Carvalho TA, Ribeiro Neto AC. Potássio na nutrição animal. Rev Eletr Nutr. 2010; 7:1280-1291. 39. NRC. National Research Council. Nutrient requeriments of dairy cattle. 8th ed. Washinton, DC.: The National Academy Press; 2021. 40. Palomares RA. Trace Minerals Supplementation with Great Impact on Beef Cattle Immunity and Health. Anim. 2022; 12:e2839. 41. Tariq M, Abbas G, Ahmad S, Mustafa R, Sultan H, Abdullah M, Hussain I, Arshad M, Cheema UB, Hassan SU. Effect of supplementation of minerals on the productive and reproductive performance of lactating cattle and buffalo. Pakistan J Sci. 2022; 74:e425. 42. Pagno KCA Barbosa JD, Salvarani FM, Bomjardim HA, Faial KCF, Souza RS, Gava A, Perotta JH, Barros Filho IR. Micromineral concentrations (copper, cobalt, iron, molybdenum and zinc) in the liver of dairy cows from Campos Gerais Region, Paraná state, Brazil. Pesq Vet Bras. 2023; 43:e07137. 43. Jeong H, Vacanti NM. Systemic vitamin intake impacting tissue proteomes. Nut Met. 2020; 17:1-16. 44. Spears JW, Weiss WP. Invited Review: Mineral and vitamin nutrition in ruminants. Appl Anim Sci. 2014; 30:180-191. 45. Erickson PS, Kalscheur KF. Nutrition and feeding of dairy cattle. Chapter 9. (pp. 157-180). In: Bazer FW, Lamb GC, Wu G, editors. Animal Agriculture. Sustainability, Challenges and Innovations. 1st ed. Elsevier Inc.: Academic Press; 2020. 46. Kareem MM, Jabir MS. Vitamins. Chapter 3. In: Imran M, Imran A, editors. Malnutrition. 1st ed. London, UK.: IntechOpen; 2020. 47. Akram M, Munir N, Daniyal M, Egbuna C, Găman MA, Onyekere PF, et al. Vitamins and minerals: Types, sources and their functions. Chapter 9. (pp 149–172). In: Egbuna C, Tupas GD, editors. Functional foods and nutraceuticals. Switzerland, AG.: Springer, Cham; 2020. 48. Marino CT, Medeiros SR. Minerais e vitaminas na nutrição de bovinos de corte. Chapter 6. (pp. 79-93). In. Medeiros SR, Gomes RC, Bungenstab DJ, editors. Nutrição de bovinos de corte: fundamentos e aplicações. Brasília, DF: Embrapa; 2015. 49. Hodnik JJ, Ježek J, Starič J. A review of vitamin D and its importance to the health of dairy cattle. J Dairy Res. 2020; 87:84–87. 50. Alves EM, Pedreira MS, Santana CA, Silva FF. Nutrição vitamínica de vacas leiteiras. Pubvet. 2008; 2:1-17. 51. Jiang Q, Lin L, Xie F, Jin W, Zhu W, Wang M, et al. Metagenomic insights into the microbe-mediated B and K2 vitamin biosynthesis in the gastrointestinal microbiome of ruminants. Microb. 2022; 10:1-16. 52. Magan JB, O’Callaghan TF, Zheng J, Zhang L, Mandal R, Hennessy D, et al. Effect of diet on the vitamin B profile of bovine milk-based protein ingredients. Foods. 2020; 9:1-17. 53. Pinedo LA, Berenchtein B, Selem ASMA. Estudo dos processos bioquímicos da fermentação, degradação e absorção de nutrientes dos alimentos em ruminantes. Pubvet. 2008; 2:1-10. 54. DA SILVA, Emanuel Isaque Cordeiro. Formulação e Avaliação de Suplemento Mineral Para Caprinos. Instrução Técnica Para o Produtor Rural de Pernambuco, v. 3, n. 1, p. 1-4, 2023. 55. DA SILVA, Emanuel Isaque Cordeiro. Nutrição Sobre a Reprodução e Fertilidade dos Bovinos. Emanuel Isaque Cordeiro da Silva, 2021. 56. DA SILVA, Emanuel Isaque Cordeiro. Suplementação e formulação de sal mineral e mistura múltipla para bovinos. Revista Universitária Brasileira, v. 2, n. 1, 2024. (shrink)

To what extent do early intuitions about ownership depend on cultural and socio-economic circumstances? We investigated the question by testing reasoning about third party ownership conflicts in various groups of three- and five-year-old children (N = 176), growing up in seven highly contrasted social, economic, and cultural circumstances (urban rich, poor, very poor, rural poor, and traditional) spanning three continents. Each child was presented with a series of scripts involving two identical dolls fighting over an object of possession. The child (...) had to decide who of the two dolls should own the object. Each script enacted various potential reasons for attributing ownership: creation, familiarity, first contact, equity, plus a control/neutral condition with no suggested reasons. Results show that across cultures, children are significantly more consistent and decisive in attributing ownership when one of the protagonists created the object. Development between three and five years is more or less pronounced depending on culture. The propensity to split the object in equal halves whenever possible was generally higher at certain locations (i.e., China) and quasi-inexistent in others (i.e., Vanuatu and street children of Recife). Overall, creation reasons appear to be more primordial and stable across cultures than familiarity, relative wealth or first contact. This trend does not correlate with the passing of false belief theory of mind. (shrink)

La vita è basata sulle opposizioni, sulla dualità. L'articolo esamina la mistica amorosa in Roland Barthes e in J.Ortega y Gasset (Amore-odio); la fenomenologia dello gnosticismo e di Emanuele Severino (Luce e Tenebra).

Agustín Serrano de Haro edita y presenta en el volumen colectivo Cuerpo vivido una selección de textos memorables en torno a lo que en 1925 fue denominado programáticamente por Ortega y Gasset una “topografía de nuestra intimidad”. La reflexión fenomenológica acerca del intracuerpo fue un tema que ha preocupado y preocupa de manera notoria a los filósofos cuyos trabajos reúne este colectivo: Ortega y Gasset, José Gaos, Joaquín Xirau, Leopoldo-Eulogio Palacios y Agustín Serrano de Haro. Pese a ello, (...) tal vez no sea tan conocido de todos nosotros el hecho de que las investigaciones filosóficas acerca del cuerpo humano (siempre sentido por uno mismo y reconocido por otros de modo intransferible) resultaron ser contribuciones pioneras y anticipaciones preclaras del tema actual del cuerpo y la corporalidad. (shrink)

Clearings of the Forest (Claros del Bosque, 1977), one of the most poetic and challenging works of María Zambrano’s thought, cannot be approached from a breathless paradigm. For the immersion in these clearings take us into the breathing of being that we contemplate alongside the more obvious physiological breathing, the breathing of life. In this work, Zambrano proposes a poetic and mystical phenomenology of the breathing of being through the breathing of its word. Thus, to recover contact with this (...) inner breathing could be to recover the lost chant of the word. This essay does not pretend to be a detailed analysis of Zambrano’s thought as a whole, nor of the vibrant mystery that her clearings reveal. The purpose is to uncover the fundamental role that breathing plays in this poetic-philosophical journey, along with other symbols such as light or love, with the question of what place this type of philosophical exercise occupies today in the classrooms of contemporary universities. (shrink)

From the back cover: "Un repaso de las publicaciones que han abordado las relaciones e intercambios entre los Estados Unidos de América y España, arroja un saldo positivo en los ámbitos sociológico, político y cultural; no así en el estricto campo de la filosofía, necesitado todavía de mayores estudios. Los once trabajos que integran Estados Unidos/España: Diálogos filosóficosrepresentan un esmerado aporte en esta dirección: el de paliar el citado desequilibrio mediante la reflexión en torno al influjo del pensamiento estadounidense en (...) España y a la recepción de la filosofía española —a través de Unamuno, Ortega y Gasset y Julián Marías— en la patria de Walt Whitman.“Es muy deseable que este activo diálogo filosófico entre los Estados Unidos y España se desarrolle todavía más en los próximos años” (cit. Jaime Nubiola). Esta ha sido la principal aspiración de esta obra: ensanchar este intercambio, esclarecer sus múltiples direcciones y abrir nuevos caminos de investigación.". (shrink)

This dissertation argues that mental representation is identical to phenomenal consciousness, and everything else that appears to be both mental and a matter of representation is not genuine mental representation, but either in some way derived from mental representation, or a case of non-mental representation.

Levels of organization and their use in science have received increased philosophical attention of late, including challenges to the well-foundedness or widespread usefulness of levels concepts. One kind of response to these challenges has been to advocate a more precise and specific levels concept that is coherent and useful. Another kind of response has been to argue that the levels concept should be taken as a heuristic, to embrace its ambiguity and the possibility of exceptions as acceptable consequences of its (...) usefulness. In this chapter, I suggest that each of these strategies faces its own attendant downsides, and that pursuit of both strategies (by different thinkers) compounds the difficulties. That both kinds of approaches are advocated is, I think, illustrative of the problems plaguing the concept of levels of organization. I end by suggesting that the invocation of levels may mislead scientific and philosophical investigations more than it informs them, so our use of the levels concept should be updated accordingly. (shrink)

This article argues that consent must be revocable. I present two arguments for this conclusion. On the argument from informed consent, irrevocable consent lacks validity because it cannot be sufficiently informed. On the argument from bodily integrity, irrevocable consent lacks validity because we do not have the authority to deny our future selves the ability to protect our bodily integrity. I explain why the argument from bodily integrity captures unique moral problems raised by irrevocable consent and illuminates an important but (...) undertheorized distinction between autonomy and bodily integrity. (shrink)

One of biology's fundamental aims is to generate understanding of the living world around—and within—us. In this chapter, I aim to provide a relatively nonpartisan discussion of the nature of explanation in biology, grounded in widely shared philosophical views about scientific explanation. But this discussion also reflects what I think is important for philosophers and biologists alike to appreciate about successful scientific explanations, so some points will be controversial, at least among philosophers. I make three main points: (1) causal relationships (...) and broad patterns have often been granted importance to scientific explanations, and they are in fact both important; (2) some explanations in biology cite the components of or processes in systems that account for the systems’ features, whereas other explanations feature large-scale or structural causes that influence a system; and (3) there can be multiple different explanations of a given biological phenomenon, explanations that respond to different research aims and can thus be compatible with one another even when they may seem to disagree. (shrink)

The tremendous philosophical focus on how to characterize explanatory metaphysical dependence has eclipsed a number of other unresolved issued about scientific explanation. The purpose of this paper is taxonomical. I will outline a number of other questions about the nature of explanation and its role in science—eight, to be precise—and argue that each is independent. All of these topics have received some philosophical attention, but none nearly so much as it deserves. Furthermore, existing views on these topics have been obscured (...) by not distinguishing among these independent questions and, especially, by not separating them from the question of what metaphysical dependence relation is explanatory. Philosophical analysis of scientific explanation would be much improved by attending more carefully to these, and probably still other, elements of an account of explanation. (shrink)

William Lycan is a notable early proponent of representationalism, which is, roughly, the view that a mental state's phenomenal features are nothing over and above its representational features (perhaps in addition to some further ingredients). Representationalism faces a challenge in accounting for perspectival experiences, which are, roughly, experiences that arise from our occupying a particular real or perceived perspective on the world. This paper presents representationalism, situating Lycan's version of representationalism within the representationalist landscape, and describes the challenge from perspectival (...) experiences. It considers three different representationalist treatments of perspectival experiences: the Layered View, which is developed by Lycan; the Relational Properties View, which Lycan eventually comes to endorse; and the Naive View, which, I will argue, combines elements from both views to achieve the best overall view. (shrink)

Positing levels of explanation has played an important role in philosophy of science. This facilitated the advocacy of antireductionism of explanations, which, at its most basic, is the idea that scientific explanations citing large (i.e. non-microphysical) entities will persist. The idea that explanations come in levels captures important features of explanatory practices, and it also does well at helping to define different positions one might take regarding explanatory reductionism or antireductionism. Yet the idea that explanations come in levels has also (...) led philosophers astray. This systematically misconstrues the relationship different explanations bear to one another, suggests candidate explanations are less numerous than they in fact are, and occludes recognition of how the selection of explanations can vary across research projects. Antireductionists about explanation should move on from talk of levels. Or so I will argue. (shrink)

Ideological language is widespread in theoretical biology. Evolutionary game theory has been defended as a worldview and a leap of faith, and sexual selection theory has been criticized for what it posits as basic to biological nature. Views such as these encourage the impression of ideological rifts in the field. I advocate an alternative interpretation, whereby many disagreements between different camps of biologists merely reflect methodological differences. This interpretation provides a more accurate and more optimistic account of the state of (...) play in the field of biology. It also helps account for biologists' tendency to embrace ideological positions. (shrink)

Many word forms in natural language are polysemous, but only some of them allow for co-predication, that is, they allow for simultaneous predications selecting for two different meanings or senses of a nominal in a sentence. In this paper, we try to explain (i) why some groups of senses allow co-predication and others do not, and (ii) how we interpret co-predicative sentences. The paper focuses on those groups of senses that allow co-predication in an especially robust and stable way. We (...) argue, using these cases, but focusing particularly on the multiply polysemous word ‘school’, that the senses involved in co-predication form especially robust activation packages, which allow hearers and readers to access all the different senses in interpretation. (shrink)

In this article, we discuss the ethics of research suspensions in animal research facilities and the consequent (mis)treatment of laboratory animals during emergencies. Through a case study from Switzerland during the COVID-19 pandemic, we articulate ethical principles and moral considerations that ought to guide the treatment and care of laboratory animals within animal research facilities during emergencies. They include a principle of preparedness, the importance of recognizing animal laboratory personnel as essential workers and conducting a Harm-Benefit Analysis in the case (...) of an emergency, assigning responsibilities in a clear way, and providing psychological support in the aftermath of an emergency. More generally, we suggest that the pandemic should be taken as a learning opportunity for critically re-evaluating and improving emergency planning within animal research institutions worldwide, in view of mitigating risks to both human and animal well-being in future emergencies. (shrink)

Several recent publications attest to a renewed interest, at the dawn of the 21st century, in the philosophy of Charles S. Peirce. While agreeing with the relevance of Peirce philosophy for the 21st century, we disagree with some interpretations of Peirce as a utilitarian-based pragmatist, or with attempts to extract from Peirce a theory of social justice for 21st century societies. A critical exploration of Peirce’s philosophy of science, particularly his idea of scientific inquiry as “the study of useless things”, (...) serves to illuminate the un-pragmatic and anti-utilitarian dimension of Peirce’s thought, as well as to reveal his true ethical relevance for the 21st century. (shrink)

Philosophers traditionally recognize two main features of mental states: intentionality and phenomenal consciousness. To a first approximation, intentionality is the aboutness of mental states, and phenomenal consciousness is the felt, experiential, qualitative, or "what it's like" aspect of mental states. In the past few decades, these features have been widely assumed to be distinct and independent. But several philosophers have recently challenged this assumption, arguing that intentionality and consciousness are importantly related. This article overviews the key views on the relationship (...) between consciousness and intentionality and describes our favored view, which is a version of the phenomenal intentionality theory, roughly the view that the most fundamental kind of intentionality arises from phenomenal consciousness. (shrink)

It is a live possibility that certain of our experiences reliably misrepresent the world around us. I argue that tracking theories of mental representation have difficulty allowing for this possibility, and that this is a major consideration against them.

Aristotle’s Poetics is the first philosophical account of an art form and is the foundational text in the history of aesthetics. The Routledge Philosophy Guidebook to Aristotle and the Poetics is an accessible guide to this often dense and cryptic work. Angela Curran introduces and assesses: Aristotle’s life and the background to the Poetics the ideas and text of the Poetics , including mimēsis ; poetic technē; the definition of tragedy; the elements of poetic composition; the Poetics’ recommendations for tragic (...) plot patterns; catharsis ; epic and comedy; the nature of our emotional response to drama; the proper pleasure of tragedy; and the role that art plays in a human life the relevance of Aristotle’s work in metaphysics, epistemology, ethics and philosophical psychology to the Poetics a comparison of Plato and Aristotle on the value of mimetic art the continuing importance of Aristotle’s Poetics to contemporary philosophy, aesthetics, and philosophy of film. (shrink)

Moods and emotions are sometimes thought to be counterexamples to intentionalism, the view that a mental state's phenomenal features are exhausted by its representational features. The problem is that moods and emotions are accompanied by phenomenal experiences that do not seem to be adequately accounted for by any of their plausibly represented contents. This paper develops and defends an intentionalist view of the phenomenal character of moods and emotions on which emotions and some moods represent intentional objects as having sui (...) generis affective properties, which happen to be uninstantiated, and at least some moods represent affective properties not bound to any objects. (shrink)

There is increasing attention to the centrality of idealization in science. One common view is that models and other idealized representations are important to science, but that they fall short in one or more ways. On this view, there must be an intermediary step between idealized representation and the traditional aims of science, including truth, explanation, and prediction. Here I develop an alternative interpretation of the relationship between idealized representation and the aims of science. In my view, continuing, widespread idealization (...) calls into question the idea that science aims for truth. I argue that understanding must replace truth as the ultimate epistemic aim of science. Additionally, science has a wide variety aims, epistemic and non-epistemic, and these aims motivate different kinds of scientific products. Finally, I show how these diverse aims---all rather distant from truth---result in the expanded influence of social values on science. (shrink)

Despite the recent proliferation of scientific, clinical, and narrative accounts of auditory verbal hallucinations, the phenomenology of voice hearing remains opaque and undertheorized. In this article, we outline an interdisciplinary approach to understanding hallucinatory experiences which seeks to demonstrate the value of the humanities and social sciences to advancing knowledge in clinical research and practice. We argue that an interdisciplinary approach to the phenomenology of AVH utilizes rigorous and context-appropriate methodologies to analyze a wider range of first-person accounts of AVH (...) at 3 contextual levels: cultural, social, and historical; experiential; and biographical. We go on to show that there are significant potential benefits for voice hearers, clinicians, and researchers. These include informing the development and refinement of subtypes of hallucinations within and across diagnostic categories; “front-loading” research in cognitive neuroscience; and suggesting new possibilities for therapeutic intervention. In conclusion, we argue that an interdisciplinary approach to the phenomenology of AVH can nourish the ethical core of scientific enquiry by challenging its interpretive paradigms, and offer voice hearers richer, potentially more empowering ways to make sense of their experiences. (shrink)

This paper compares tracking and phenomenal intentionality theories of intentionality with respect to the issue of naturalism. Tracking theories explicitly aim to naturalize intentionality, while phenomenal intentionality theories generally do not. It might seem that considerations of naturalism count in favor of tracking theories. We survey key considerations relevant to this claim, including some motivations for and objections to the two kinds of theories. We conclude by suggesting that naturalistic considerations may in fact support phenomenal intentionality theories over tracking theories.

The concept of hierarchical organization is commonplace in science. Subatomic particles compose atoms, which compose molecules; cells compose tissues, which compose organs, which compose organisms; etc. Hierarchical organization is particularly prominent in ecology, a field of research explicitly arranged around levels of ecological organization. The concept of levels of organization is also central to a variety of debates in philosophy of science. Yet many difficulties plague the concept of discrete hierarchical levels. In this paper, we show how these difficulties undermine (...) various implications ascribed to hierarchical organization, and we suggest the concept of scale as a promising alternative to levels. Investigating causal processes at different scales offers a way to retain a notion of quasi-levels that avoids the difficulties inherent in the classic concept of hierarchical levels of organization. Throughout, our focus is on ecology, but the results generalize to other invocations of hierarchy in science and philosophy of science. (shrink)

Scientific realism is a thesis about the success of science. Most traditionally: science has been so successful at prediction and guiding action because its best theories are true (or approximately true or increasing in their degree of truth). If science is in the business of doing its best to generate true theories, then we should turn to those theories for explanatory knowledge, predictions, and guidance of our actions and decisions. Views that are popular in contemporary philosophy of science about scientific (...) modeling and the centrality of idealization create several challenges for this traditional form of scientific realism. Yet the basic idea behind scientific realism that science has been and will continue to be epistemically successful is deeply appealing. This chapter explores the challenges posed by idealization and scientific modeling to motivate a scientific realism fully divorced from the idea that science is in the business of generating true theories. On the resulting view, the objects of scientific knowledge are causal patterns, so this knowledge only ever provides partial, simplified accounts of a complex reality. This variety of selective realism better accommodates the nature of our present-day scientific successes and offers an interpretation of scientific progress that resists the antirealist’s pessimism. (shrink)

An historically important conception of the unity of science is explanatory reductionism, according to which the unity of science is achieved by explaining all laws of science in terms of their connection to microphysical law. There is, however, a separate tradition that advocates the unity of science. According to that tradition, the unity of science consists of the coordination of diverse fields of science, none of which is taken to have privileged epistemic status. This alternate conception has roots in Otto (...) Neurath’s notion of unified science. In this paper, I develop a version of the coordination approach to unity that is inspired by Neurath’s views. The resulting conception of the unity of science achieves aims similar to those of explanatory reductionism, but does so in a radically different way. As a result, it is immune to the criticisms facing explanatory reductionism. This conception of unity is also importantly different from the view that science is disunified, and I conclude by demonstrating how it accords better with scientific practice than do conceptions of the disunity of science. (shrink)

The predominant view is that a study using health data is observational research and should require individual consent unless it can be shown that gaining consent is impractical. But recent arguments have been made that citizens have an ethical obligation to share their health information for research purposes. In our view, this obligation is sufficient ground to expand the circumstances where secondary use research with identifiable health information is permitted without explicit subject consent. As such, for some studies the Institutional (...) Review Board/Research Ethics Committee review process should not assess the practicality of gaining consent for data use. Instead the review process should focus on assessing the public good of the research, public engagement and transparency. (shrink)

In his chapter in this volume, Christopher Pincock develops an argument for scientific realism based on scientific understanding, and he argues that Giere’s (2006) and my (2017, 2020) commitment to the context-dependence of scientific understanding or knowledge renders our views unable to account for an essential step in how scientists come to know. Meanwhile, in my chapter in this volume, I motivate a view that I call "causal pattern realism." In this response to Pincock's chapter, I will sketch a revised (...) version of Pincock’s argument for realism that is consistent with causal pattern realism. Then I will respond to Pincock’s concern that the context-dependence of understanding on my view would interfere with the scientific community’s ability to extrapolate from specific experimental and observational contexts as needed to develop knowledge. My goal is not to convince anyone to be a causal pattern realist but rather to create the space for such a view, taking into account the concerns motivating Pincock. (shrink)

In this paper, I first outline the view developed in my recent book on the role of idealization in scientific understanding. I discuss how this view leads to the recognition of a number of kinds of variability among scientific representations, including variability introduced by the many different aims of scientific projects. I then argue that the role of idealization in securing understanding distances understanding from truth, but that this understanding nonetheless gives rise to scientific knowledge. This discussion will clarify how (...) my view relates to three other recent books on understanding by Henk de Regt, Catherine Elgin, and Kareem Khalifa. (shrink)

This article aims to indicate possible approximations between the Lacanian concept of object a and the Winnicottian concept of transitional object. Initially, the Lacanian references to Winnicott’s work are mostly critics, e.g. in the Seminar 4 (1956-1957/1995), which debates the issue of object relation. Nevertheless, a few years later, in the Seminar 15 (1967-1968), an association between the object a and the transitional object is explicitly stated by Lacan, accompanied by a strong recognition of the English psychoanalyst’s work. Through this (...) demarche, it should be clear the importance of the objects to the subjective constitution from the point of view of a psychoanalytical theory. Keywords: transitional object; object a; object relation; Winnicott; Lacan. (shrink)

The purpose of this article is to show that animal rights are not necessarily at odds with the use of animals for research. If animals hold basic moral rights similar to those of humans, then we should consequently extend the ethical requirements guiding research with humans to research with animals. The article spells out how this can be done in practice by applying the seven requirements for ethical research with humans proposed by Ezekiel Emanuel, David Wendler and Christine Grady to (...) animal research. These requirements are i) social value, ii) scientific validity, iii) independent review, iv) fair subject selection, v) favorable risk-benefit ratio, vi) informed consent, and vii) respect for research subjects. In practice, this means that we must reform the practice of animal research to make it more similar to research with humans, rather than completely abolish the former. Indeed, if we banned animal research altogether, then we would also deprive animals of its potential benefits – which would be ethically problematic. (shrink)

Over 60% of all epidemics have a zoonotic origin, that is, they result from the transmission of infectious diseases from animals to humans. The spill-over of diseases often happens because humans exploit and use animals. In this article, I outline the four most common interfaces that favour the emergence and spread of zoonotic infectious diseases: wildlife hunting, small-scale farming, industrialised farming practices and live animal markets. I analyse which practices serve human food security – and thus have a non-trivial purpose (...) – and which predominantly have an economic purpose or serve as a symbol of wealth. I conclude that many practices that increase the risk for zoonotic infectious disease outbreaks actually do not contribute to the survival and food security of humans. I make two arguments in turn. First, I argue that in cases where the consumption and use of animal products does not contribute to the food security of a population, then this population has a duty to abstain from them, since they impose a grave and avoidable risk to themselves as well as to innocent third-parties. However, some communities must sometimes rely on practices that increase the risk of emergence and transmission of zoonotic infectious diseases, because they have no healthy alternatives. That is, the food security of the local population depends on the consumption and use of risky animal products. The second argument I advance is that, in such scenarios, the international community has a duty to provide the communities concerned with alternative food options, as well as economic and educational opportunities and technologies, in order to reduce the spill-over risk of infectious diseases. Given that abstention from such practices contributes signifcantly to the public good and benefits the international community, the latter has a corresponding duty to provide local communities which abandon such practices with alternatives. (shrink)

Causal accounts of scientific explanation are currently broadly accepted (though not universally so). My first task in this paper is to show that, even for a causal approach to explanation, significant features of explanatory practice are not determined by settling how causal facts bear on the phenomenon to be explained. I then develop a broadly causal approach to explanation that accounts for the additional features that I argue an explanation should have. This approach to explanation makes sense of several aspects (...) of actual explanatory practice, including the widespread use of equilibrium explanations, the formulation of distinct explanations for a single event, and the tight relationship between explanations of events and explanations of causal regularities. (shrink)

Resumen: El diálogo fallido entre Estado y pueblo mapuche se enraíza en la formación misma del Estado chileno promovido por una elite que construye una institucionalidad a su imagen y semejanza, ilusamente homogénea e invisibilizadora de las diferencias. No obstante, el mismo espíritu “civilizador” que espera integrar a estas minorías asimilándolas, facilita la inserción de estas minorías en el diálogo postmoderno acerca de la interculturalidad, en el cual se enfrentan a la perspectiva multiculturalista que no da cuenta del acto de (...) reconocimiento que implica convivir con la otredad. (shrink)

Suele ser decepcionante asistir a la conferencia de algún/a filósofo/a u otro/a pensador/a, artista si es que uno ya lo ha leído, estudiado o seguido su obra por algún tiempo. Leer Sin miedo no ha sido la excepción. De ahí el valor de una reseña de libro, a saber: definir la audiencia para la cual el texto comentado podría ser un aporte. En este sentido, Sin miedo es perfecto para un público poco familiarizado con la obra de Butler o que (...) todavía no la ha estudiado en profundidad, aunque sí le interesa conocerla. Probablemente este libro abre el apetito por ahondar en la propuesta de Butler, que se desarrolla prolíficamente en su vasta escritura. Sin miedo es una publicación que agrupa cinco conferencias que la filósofa dictó entre los años 2018 y 2019, en ciudades como Berlín, Guadalajara, Ciudad de México, La Habana, Buenos Aires y Santiago de Chile. En cada una de ellas, Judith Butler hace un guiño al lugar en el que habla. Es respetuosa de la audiencia y eso marca sus dichos, que concilian el pensamiento elaborado y complejo con una escucha menos enmarcada en el canon académico. Es fácil detectar en estas conferencias ciertos temas que las recorren transversalmente y de los que la autora ha dado cuenta en sus últimas publicaciones: la violencia política que se ejerce hacia determinados grupos de nuestra sociedad, la común vulnerabilidad como un factor que pone en evidencia tanto la interdependencia como la posibilidad de la acción política, y el énfasis que expone respecto de la desigual distribución de la vulnerabilidad, así como de la necesidad de luchar por una democracia que Butler define como radical. (shrink)

Michael Strevens offers an account of causal explanation according to which explanatory practice is shaped by counterbalanced commitments to representing causal influence and abstracting away from overly specific details. In this paper, I challenge a key feature of that account. I argue that what Strevens calls explanatory frameworks figure prominently in explanatory practice because they actually improve explanations. This suggestion is simple but has far-reaching implications. It affects the status of explanations that cite multiply realizable properties; changes the explanatory role (...) of causal factors with small effect; and undermines Strevens’ titular explanatory virtue, depth. This results in greater coherence with explanatory practice and accords with the emphasis that Strevens places on explanatory patterns. Ultimately, my suggestion preserves a tight connection between explanation and the creation of understanding by taking into account explanations’ role in communication. (shrink)

A common argument against explanatory reductionism is that higher‐level explanations are sometimes or always preferable because they are more general than reductive explanations. Here I challenge two basic assumptions that are needed for that argument to succeed. It cannot be assumed that higher‐level explanations are more general than their lower‐level alternatives or that higher‐level explanations are general in the right way to be explanatory. I suggest a novel form of pluralism regarding levels of explanation, according to which explanations at different (...) levels are preferable in different circumstances because they offer different types of generality, which are appropriate in different circumstances of explanation. (shrink)

One of the central aims of science is explanation: scientists seek to uncover why things happen the way they do. This chapter addresses what kinds of explanations are formulated in biology, how explanatory aims influence other features of the field of biology, and the implications of all of this for biology education. Philosophical treatments of scientific explanation have been both complicated and enriched by attention to explanatory strategies in biology. Most basically, whereas traditional philosophy of science based explanation on derivation (...) from scientific laws, there are many biological explanations in which laws play little or no role. Instead, the field of biology is a natural place to turn for support for the idea that causal information is explanatory. Biology has also been used to motivate mechanistic accounts of explanation, as well as criticisms of that approach. Ultimately, the most pressing issue about explanation in biology may be how to account for the wide range of explanatory styles encountered in the field. This issue is crucial, for the aims of biological explanation influence a variety of other features of the field of biology. Explanatory aims account for the continued neglect of some central causal factors, a neglect that would otherwise be mysterious. This is linked to the persistent use of models like evolutionary game theory and population genetic models, models that are simplified to the point of unreality. These explanatory aims also offer a way to interpret many biologists’ total commitment to one or another methodological approach, and the intense disagreements that result. In my view, such debates are better understood as arising not from different theoretical commitments, but commitments to different explanatory projects. Biology education would thus be enriched by attending to approaches to biological explanation, as well as the unexpected ways that these explanatory aims influence other features of biology. I suggest five lessons for teaching about explanation in biology that follow from the considerations of this chapter. (shrink)

Debate about cognitive science explanations has been formulated in terms of identifying the proper level(s) of explanation. Views range from reductionist, favoring only neuroscience explanations, to mechanist, favoring the integration of multiple levels, to pluralist, favoring the preservation of even the most general, high-level explanations, such as those provided by embodied or dynamical approaches. In this paper, we challenge this framing. We suggest that these are not different levels of explanation at all but, rather, different styles of explanation that capture (...) different, cross-cutting patterns in cognitive phenomena. Which pattern is explanatory depends on both the cognitive phenomenon under investigation and the research interests occasioning the explanation. This reframing changes how we should answer the basic questions of which cognitive science approaches explain and how these explanations relate to one another. On this view, we should expect different approaches to offer independent explanations in terms of their different focal patterns and the value of those explanations to partly derive from the broad patterns they feature. (shrink)

Reliable misrepresentation is getting things wrong in the same way all the time. In Mendelovici 2013, I argue that tracking theories of mental representation cannot allow for certain kinds of reliable misrepresentation, and that this is a problem for those views. Artiga 2013 defends teleosemantics from this argument. He agrees with Mendelovici 2013 that teleosemantics cannot account for clean cases of reliable misrepresentation, but argues that this is not a problem for the views. This paper clarifies and improves the argument (...) in Mendelovici 2013 and response to Artiga's arguments. Tracking theories, teleosemantics included, really do need to allow for clean cases of reliable misrepresentation. (shrink)

Escribir hoy en día un libro sobre hermenéutica, que tal hermenéutica se refiera a la desarrollada por G. Gadamer en su conocido Verdad y método y que se pretenda añadir algo nuevo a lo mucho escrito sobre el tema parecería, a primera vista, empresa irrealizable. Que ambas pretensiones inspiren la sólida monografía de María G. Navarro —titulada Interpretar y argumentar— constituye empresa audaz y arriesgada, plena de coraje innovador, que provoca admiración, curiosidad e interés. Contra lo que pudiera parecer (...) a primera vista, el libro contiene un alto componente de originalidad y creatividad, debido a la estratagema metodoló-gica de que se sirve la autora. A saber, una hermenéutica in obliquo, estrategia consistente en interpretar a la hermenéutica gadameriana a través del prisma de la lógica de la argumentación. (shrink)

David Papineau’s _The Metaphysics of Sensory Experience_ is deep, insightful, refreshingly brisk, and very readable. In it, Papineau argues that sensory experiences are intrinsic and non-relational states of subjects; that they do not essentially involve relations to worldly facts, properties, or other items (though they do happen to correlate with worldly items); and that they do not have truth conditions simply in virtue of their conscious (i.e., phenomenal) features. I am in enthusiastic agreement with the picture as described so far. (...) But Papineau also argues that sensory experiences are in no interesting sense essentially representational and that what is responsible for their truth conditions is their correlations with the environment. Here, I disagree. Indeed, I think Papineau does not follow his arguments to their proper conclusions. For if sensory experiences are intrinsic, non-relational, and only contingently correlated with worldly conditions (as Papineau and I agree they are), then the phenomenal features of sensory states are representational in an important sense: they constitute what we think, perceptually experience, or otherwise entertain, making up how things seem to us from a first-person perspective. Because of this, the truth conditions of perceptual experiences cannot be entirely independent of their phenomenal features. They cannot merely be a matter of environmental correlations. If we follow Papineau’s arguments to their proper conclusions, we end up with a view much closer to a version of representationalism that Papineau dismisses, a view he calls “pure phenomenal intentionalism”. (shrink)

I argue that the discussion around the True Preferences Knowledge Problem in behavioral welfare economics has suffered from a missing distinction between two different knowledge problems: one about welfare, and the other about public policy. Here, I separate those knowledge problems and show that, given their different success conditions, it is no surprise that we haven’t found a satisfactory answer to “the” true preferences knowledge problem. There is an embedded tendency to try to answer the policy knowledge problem by engaging (...) the welfare knowledge problem. I show that the impulse is misguided, and that we do not need to appeal to a complete theory of how preferences are related to welfare to answer questions about policy. However, this does not mean that we need to stop talking about preferences. We can make progress on the policy knowledge problem without appealing to a theory of welfare by focusing on the information that people are giving us about the mistakes they are making. I introduce repudiated preferences as a device that allows us to break out of this cycle and start to make progress in our discussions of nudging and Behavioral Intervention Policies without first solving the welfare knowledge problem. Finally, I acknowledge the challenges that still face this approach, and trace some avenues for how further work could build on these insights. (shrink)

The value of optimality modeling has long been a source of contention amongst population biologists. Here I present a view of the optimality approach as at once playing a crucial explanatory role and yet also depending on external sources of confirmation. Optimality models are not alone in facing this tension between their explanatory value and their dependence on other approaches; I suspect that the scenario is quite common in science. This investigation of the optimality approach thus serves as a case (...) study, on the basis of which I suggest that there is a widely felt tension in science between explanatory independence and broad epistemic interdependence, and that this tension influences scientific methodology. (shrink)

According to intentionalism, phenomenal properties are identical to, supervenient on, or determined by representational properties. Intentionalism faces a special challenge when it comes to accounting for the phenomenal character of moods. First, it seems that no intentionalist treatment of moods can capture their apparently undirected phenomenology. Second, it seems that even if we can come up with a viable intentionalist account of moods, we would not be able to motivate it in some of the same kinds of ways that intentionalism (...) about other kinds of states can be motivated. In this article, I respond to both challenges: First, I propose a novel intentionalist treatment of moods on which they represent unbound affective properties. Then, I argue that this view is indirectly supported by the same kinds of considerations that directly support intentionalism about other mental states. (shrink)

The optimality approach to modeling natural selection has been criticized by many biologists and philosophers of biology. For instance, Lewontin (1979) argues that the optimality approach is a shortcut that will be replaced by models incorporating genetic information, if and when such models become available. In contrast, I think that optimality models have a permanent role in evolutionary study. I base my argument for this claim on what I think it takes to best explain an event. In certain contexts, optimality (...) and game-theoretic models best explain some central types of evolutionary phenomena. ‡Thanks to Michael Friedman, Helen Longino, Michael Weisberg, and especially Elliott Sober for comments on earlier drafts of this paper. †To contact the author, please write to: Department of Philosophy, Stanford University, Stanford, CA 94305-2155; e-mail: [email protected]. (shrink)

Scientific explanations must bear the proper relationship to the world: they must depict what, out in the world, is responsible for the explanandum. But explanations must also bear the proper relationship to their audience: they must be able to create human understanding. With few exceptions, philosophical accounts of explanation either ignore entirely the relationship between explanations and their audience or else demote this consideration to an ancillary role. In contrast, I argue that considering an explanation’s communicative role is crucial to (...) any satisfactory account of explanation. (shrink)

Propositionalism is the view that all intentional states are propositional states, which are states with a propositional content, while objectualism is the view that at least some intentional states are objectual states, which are states with objectual contents, such as objects, properties, and kinds. This paper argues that there are two distinct ways of understanding propositionalism and objectualism: (1) as views about the deep nature of the contents of intentional states, and (2) as views about the superficial character of the (...) contents of intentional states. I argue that we should understand the views in the second way. I also argue that the propositionalism debate is fairly independent from debates over the deep nature of intentionality, and that this has implications for arguments for propositionalism and objectualism from claims about the nature of intentional content. I close with a short discussion of how related points apply to the debate over singular content. (shrink)